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  • Essay / chromosomal abnormality - 1152

    When every child is born, he or she is born with two sets of chromosomes. 23 chromosomes come from the mother and 23 chromosomes from the father, making a total of 46 chromosomes for the child. But some children born today are born with chromosomal abnormalities. Chromosome abnormalities involve the sex chromosomes and are sex specific (O'Neil). Thanks to current technology and previous studies, we are able to determine chromosomal abnormalities and the syndromes formed by these abnormalities. Chromosomal abnormalities occur when there is a problem in cell division. There are two types of cell division: mitosis and meiosis. Mitosis is the process by which two daughter cells, each having the same number and type of chromosomes as the parent nucleus, divide into identical cells. They undergo this change in four phases. These phases are called Prophase, Metaphase, Anaphase and Telophase. Meiosis is where the daughter cell has half the number of chromosomes as the parent cells and involves the division of two cells and therefore produces four daughter cells. Meiosis undergoes the same phases as mitosis but undergoes twice. “In both processes, the correct number of chromosomes are expected to end up in the resulting cells. However, errors in cell division can result in cells containing too few or too many copies of a chromosome. Errors can also occur when duplicating chromosomes” (Genome). There are many types of chromosomal abnormalities that can be classified into two basic groups. The first group consists of numerical anomalies that occur “when an individual is either missing one chromosome from a pair (monosomy) or has more than two chromosomes from a pair (trisomy)” (Genome ). The second group is called structural anomalies. "Structural abnormalities occur when chromosome morphology is altered due to unusual location