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  • Essay / Cost-effectiveness analysis of coronary artery bypass grafting...

    IntroductionCoronary artery disease is a heart disease characterized by narrow arteries and restricted blood flow in the arteries and is the leading cause of morbidity and mortality in the global scale.[1] According to WHO estimates, 6.8% of men and 5.3% of women are affected globally.[2-4] Cardiovascular diseases account for 29% of all deaths in Canada; of all cardiovascular deaths, 54% and 23% were due to ischemic heart disease and heart attack, respectively. The total cost of heart disease and stroke was more than $20.9 billion each year. [5,6] With more than one artery affected, multivessel coronary artery disease is more complex and more likely to be accompanied by other comorbidities, including diabetes or high blood pressure; Multivessel coronary artery disease is generally more difficult to treat, has a poorer prognosis, and is more expensive than single coronary artery disease. [7]Revascularization strategies, including coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI), are recommended as treatments for coronary artery disease. [8-11] PAC generally costs more ...