Hypertrophic Cardiomyopathy: Effects on Young Athletes Alyssa Trimm 130568370 Wilfrid Laurier University Dr. Kalmar KP 122 Section AHypertrophic cardiomyopathy is a genetic disease of the heart, which causes the heart muscle to become thick and strong. The thick muscle causes the chamber to decrease in size, causing the heart to pump less blood. Hypertrophic cardiomyopathy is a leading cause of sudden death because the prevention of blood flow causes cardiac arrest. More fruitful research is being carried out on HCM, including research on associated genetics and inheritance of genes. Unfortunately, this disorder affects many young athletes due to the increased stress of training on their hearts. However, despite the use of new technologies such as electrocardiogram and transthoracic echocardiogram, strategies are limited, limiting new responses. This disease is said to begin within the sacromeric proteins, as previous studies have called this disorder “sacromeric disease.” 6. The muscle around the left ventricle is so strong that it does not relax enough after contraction to replenish blood in the heart. 5. Hypertrophic cardiomyopathy has been found in approximately 50% of young people who die suddenly. 5. A recent study observed genes associated with hypertrophic cardiomyopathy. In 20 genes related to the sacromere and myofilament, 1,400 mutations were noted in HCM 6. Mutations within the sacromere prevent the normal shortening that causes the muscle to contract more, thereby reducing relaxation. However, it is not proven that all mutated genes cause hypertrophy. The MYH7 gene seems to be the most common since 25 to 35% of patients with mild or severe HCM presented this gene 6. Despite...... middle of article...... cardiomyopathy cohort. Hellenic J Cardiol. July-August 2013; 54(4):281-8.Dassen WRM, Kuipers H, Mihl C et al. Cardiac remodeling: concentric versus eccentric hypertrophy in strength and endurance athletes. Neth Heart J. April 2008; 16(4):129-133. De Cecoo CN, Magri D, Piccirillo G, et al. Dispersion of myocardial repolarization and late gadolinium enhancement in patients with hypertrophic cardiomyopathy. Circulation Journal. March 2014Efthimiadis GK, Pagourelias ED, Pitsis A, et al. Surgical septal myectomy for hypertrophic cardiomyopathy in Greece: a first single-center experience. Hellenic J Cardiol. Mar-April 2014;55(2):132-8.Rowland T. Sudden unexpected death in young athletes: reconsidering “hypertrophic cardiomyopathy.” PEDIATRICS, April 2009;123(4):1217-1222. Tang W, Yingchoncharoen T. Recent advances in hypertrophic cardiomyopathy. F1000Prime Rep. FEBRUARY 2104;3;6;12.