Introduction: Onchocerciasis is a disease of public health and socio-economic importance in Ethiopia. Onchocerciasis, commonly known as "river blindness", is caused by the parasitic worm Onchocerca volvulus and is transmitted to humans through the bite of an infected black fly. The transmitted worm larvae develop into adults and settle in the fibrous nodules of the human body and produce microfilariae. Prolonged infection with the parasitic worm can lead to blindness and skin depigmentation. Onchocerciasis mainly affects the southwestern region of Ethiopia, Africa and the Americas (World Health Organization, 2006) and the life cycle and mode of entry: The life cycle of O. volvulus is complex and depends largely on the black fly. The life cycle has many stages that could be interrupted to avoid contracting the disease. The life cycle is as follows: 1. During a bite, an infected black fly (genus Simulium) introduces third instar larvae onto the human skin, where they enter the bite wound2. In skin tissues, larvae develop into adults, which usually exist in nodules of skin connective tissues3. Adults can live in the nodules for about 15 years. Some nodules may contain numerous male and female worms.4. A black fly ingests the microfilariae during a blood meal.5. After ingestion, microfilariae migrate from the midgut of the blackfly through the hemocoel to the thoracic muscles.6. There, the microfilariae develop into first instar larvae7. And then into third instar infective larvae.8. The third instar infective larvae migrate towards the black fly's proboscis9. And can infect another human when the fly takes another blood meal.Current effects and treatments:The O. volvulus worm has several...... middle of paper ......vention, 2013). Other preventive measures volunteers can use include covering their skin; wearing long sleeved tops and long pants is essential, this will prevent the black fly from biting the individual. If volunteers use these small prevention measures, they will be able to avoid being bitten and infected. Conclusion: In conclusion, eradication of onchocerciasis in Ethiopia is highly possible and probable with the help of volunteer groups such as this to help and assist small villages and communities to educate them on how to avoid getting infected. The group of volunteers will be able to sufficiently avoid infection if a few simple steps are followed and extra precautions are taken. It can be predicted that with education of communities throughout Ethiopia, eradication of the disease is very likely..