The purpose of this article is to review and evaluate two recent studies, published within the last 5 years, conducted on the induction of therapeutic hypothermia slight in relation to cardiac and vascular circulation. One article tested and evaluated the effects of mild hypothermia treatment on patients with cardiogenic shock after out-of-hospital cardiac arrest resuscitation. The other study provides information about hypothermia treatment on the cardiac index of postoperative cardiac surgical patients after ice-cold and room temperature injections during hypothermic and normothermic body temperatures. Additionally, given that previous studies have concluded that mild inductions of hypothermia help improve long-term neurological outcomes, each article discusses the significant benefit of using therapeutic hypothermia, particularly in the increased survival rate after out-of-hospital sudden cardiac arrest. According to Joint Commission in 2011, more than 290,000 people in the United States experience sudden cardiac arrest each year. The survival rate of victims remains low and the risk of reoffending remains a major concern for most survivors, where only 7-8.5% survive (Joint Commission, 2011). If resuscitation efforts fail to restore cerebral blood flow within minutes of cardiac arrest, hypoxia can lead to permanent brain damage. Even if circulation is restored, secondary brain damage can occur following direct tissue damage or disruption of the blood-brain barrier (Michelle et al, 2011). Thus, with the aim of improving survival rates, preventing permanent neurological damage and reducing mortality among survivors of cardiac arrest, clinical experiments have shown that a state of mild hypothermia of approximately 32° C at 34°C reduces metabolism and oxygen..... .middle of paper...and how. American Nurse Today 6(7). Retrieved from http://www.americannursetoday.com/article.aspx?id=8014&fid=7986Joint Commission (2011). Sudden cardiac arrest: meeting the challenge. Retrieved from http://www.jointcommission.org/assets/1/6/Sudden_Cardiac_Arrest-final_2.pdfWalsh, E., Adams, S., Chernipeski, J., Cloud, J., Gillies, E., Fox, R ., Luckeroth, P. Rice, M., Salamanca, C., Sherman, B., Nezworski, A. and Ash, T. (2009). Iced or room temperature injectates for measurement of cardiac index during hypothermia and normothermia. American Journal of Critical Care 19(4), 365-372. http://dx.doi.org/10.4037/ajcc2009255 Zobel, C., Adler, C., Kranz, A., Seck, C., Pfister, R., Hellmich, M., Kochanek, M. and Reuter, H (2012). Mild therapeutic hypothermia in cardiogenic shock syndrome. Intensive Care Medicine, 40(6), 1715-1723. http://dx.doi.org/10.1097/CCM.0b013e318246b820