Divorce, marital conflict, social isolation, relationships with primary confidants, and relationship problems are a big problem with social groups in which a patient does not is not educated and is not willing to be his support. . The patient must be willing to change the people around him and make choices to receive strong support. Your support team should be able to see the signs of mood and personality changes. Bipolar mania or depression can come on suddenly and getting care right away could mean the difference between life and living.