Nutrition and depression are intimately and undeniably linked, as growing evidence from neuropsychiatry researchers suggests. Supplementing with nine vitamins, 10 times the normal recommended dietary allowance (RDA) for a year, improved mood in both men and women, according to a study published in Neuropsychobiology. What's interesting is that these mood changes after a year occurred even though the blood status of nine vitamins reached a plateau after 3 months. This improvement in mood was particularly associated with an improvement in vitamin B2 and B6 status. In women, baseline vitamin B1 status was linked to poor mood and improvement after 3 months was associated with better mood. Thiamine (vitamin B1) is known to modulate cognitive performance, particularly in the geriatric population. Say no to plagiarism. Get a tailor-made essay on “Why Violent Video Games Should Not Be Banned”? Get the original essay Clinical trials have indicated that vitamin B12 (cynobalamin) delays the onset of signs of dementia (and blood abnormalities), if administered in a specific clinical time window, before symptoms first appear. . Cobalamin supplementation improves brain and cognitive functions in older adults; it frequently promotes the functioning of factors related to the frontal lobe, in addition to the linguistic function of people with cognitive disorders. Adolescents who have borderline levels of vitamin B12 deficiency develop signs of cognitive changes. The vital role of folate in brain metabolic processes has been recognized by many researchers who have noted that depressive symptoms are the most common neuropsychiatric manifestation of folate deficiency. It has been observed that patients suffering from depression have blood levels of folate (vitamin B9) that are, on average, 25% lower than those of healthy controls. Low folate levels have also been identified as an important predisposing factor for poor antidepressant treatment outcomes. A controlled study reportedly showed that 500 mcg of folic acid improved the effectiveness of antidepressants. The essential role of folate in brain metabolic pathways has been well recognized by various researchers who have noted that depressive symptoms constitute the most common neuropsychiatric manifestation of folate deficiency. It is not yet clear whether poor diet, as a symptom of depression, causes folate deficiency or whether primary folate deficiency produces depression and its symptoms. Keep in mind: this is just a sample. Get a personalized article from our expert writers now. Get a personalized article trialRandomized, controlled trials involving folate and B12 suggest that patients treated with 0.8 mg folic acid/day or 0.4 mg vitamin B12 per day will experience a reduction in symptoms of depression. Epidemiological evidence shows that vitamin D deficiency is associated with an 8-14% increase in depression and a 50% increase in suicide; however, the causality and effectiveness of supplementation remain controversial pending confirmation by systematic review and meta-analysis..