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  • Essay / The Immune System: The Innate System and the Immune System

    First, mast cells, again, originate from an individual's bone marrow and focus primarily on the individual's tissues (Sherwood et al. , 2014). They contain many important chemicals that support the inflammatory response and support regular infections and allergic reactions (“About Mast Cells…”, n.d.). Monocytes have the ability to transform into macrophages and dendritic cells, but I'll get to that later. The main function of a monocyte is to mature into its subsequent counterparts (Sherwood et al., 2014). Think of it as a stepping stone to macrophages and dendritic cells. Macrophages are much larger than monocytes, hence their name. They work by finding a pathogen and ingesting it through phagocytosis (Sherwood et al., 2014). A macrophage can be classified into two different types: M1 and M2. M1 macrophages are incredibly aggressive when presented with a pathogen, and as a result, the body reacts with an acute inflammatory response. M2 macrophages act in the opposite way: they react a little more slowly to pathogens and their inflammatory response is much weaker in comparison (Promo Cell, 2014). Next, dendritic cells are very similar to macrophages because they are related to each other. Another reason they are similar is that they help connect answers.